The evolutionary divergence of neurotransmitter receptors and second-messenger pathways.

doi:10.1007/BF00174044

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Article

The evolutionary divergence of neurotransmitter receptors and second-messenger pathways.

Journal of molecular evolution - 1 Jul 1995

Fryxell K J

Abstract excerpt

Members of the superfamily of G-protein-coupled neurotransmitter receptors have a conserved secondary structure, a moderate and reasonably steady rate of sequence change, and usually lack introns within the coding sequence. These properties are advantageous for evolutionary studies. The duplicati...

Topics

Adenylyl Cyclases
Animals
Biological Evolution
GTP-Binding Proteins
Genetic Variation
Humans
Phylogeny
Protein Structure, Secondary
Receptors, Adrenergic
Receptors, Dopamine
Receptors, Muscarinic
Receptors, Neurotransmitter
Second Messenger Systems
Time

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