Article
Large variation in detection of histidine-rich protein 2 in Plasmodium falciparum isolates from Colombia.
The American journal of tropical medicine and hygiene - 1 Oct 2010
Pava Zuleima, Echeverry Diego F, Díaz Gustavo, Murillo Claribel
Abstract excerpt
Most rapid diagnostic tests (RDTs) available use histidine-rich protein 2 (HRP2) as a target. However, it has been reported that sequence variations of this protein affects its sensitivity. Currently, there is insufficient evidence for HRP2 variability in Plasmodium falciparum isolates from Colombia and its relationship with RDT performance. To determine possible geographic differences and their effects on the...
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