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Article

Sibling recurrence and the genetic epidemiology of autism.

The American journal of psychiatry - 1 Nov 2010

Constantino John N, Zhang Yi, Frazier Thomas, Abbacchi Anna M, Law Paul

Abstract excerpt

OBJECTIVE: Although the symptoms of autism exhibit quantitative distributions in nature, estimates of recurrence risk in families have never previously considered or incorporated quantitative characterization of the autistic phenotype among siblings. METHOD: The authors report the results of quantitative characterization of 2,920 children from 1,235 families participating in a national volunteer register, with at...

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Share to Child Development Disorders, Pervasive
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20889652
DOI: 10.1176/appi.ajp.2010.09101470
PMCID: PMC2970737

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