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Article

Familial aggregation of quantitative autistic traits in multiplex versus simplex autism.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2009

Virkud Yamini V, Todd Richard D, Abbacchi Anna M, Zhang Yi, Constantino John N

Abstract excerpt

Recent research has suggested that the mode of inheritance for simplex autism (SA, one individual in the family affected) may be distinct from that for multiplex autism (MA, two or more individuals affected). Since sub clinical autistic traits have been observed in "unaffected" relatives of children with autism, we explored whether the distributions of such traits in families supported differential modes of...

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Identifiers

PMID: 18618672
DOI: 10.1002/ajmg.b.30810
PMCID: PMC2819431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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