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Article

Quantitative trait variation in ASD probands and toddler sibling outcomes at 24 months.

Journal of neurodevelopmental disorders - 5 Feb 2020

Girault Jessica B, Swanson Meghan R, Meera Shoba S, Grzadzinski Rebecca L, Shen Mark D, Burrows Catherine A, Wolff Jason J, Pandey Juhi, John Tanya St, Estes Annette, Zwaigenbaum Lonnie, Botteron Kelly N, Hazlett Heather C, Dager Stephen R, Schultz Robert T, Constantino John N, Piven Joseph

Abstract excerpt

BACKGROUND: Younger siblings of children with autism spectrum disorder (ASD) are at increased likelihood of receiving an ASD diagnosis and exhibiting other developmental concerns. It is unknown how quantitative variation in ASD traits and broader developmental domains in older siblings with ASD (probands) may inform outcomes in their younger siblings. METHODS: Participants included 385 pairs of toddler siblings...

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Identifiers

PMID: 32024459
DOI: 10.1186/s11689-020-9308-7
PMCID: PMC7003330

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