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Article

A quantitative trait locus analysis of social responsiveness in multiplex autism families.

The American journal of psychiatry - 1 Apr 2007

Duvall Jacqueline A, Lu Ake, Cantor Rita M, Todd Richard D, Constantino John N, Geschwind Daniel H

Abstract excerpt

OBJECTIVE: Autism is a complex genetic disorder with a highly heterogeneous phenotype defined by repetitive behaviors, language deficits, and problems with reciprocal social interactions. The authors present the first genome-wide scan for a social endophenotype in autism using the Social Responsiveness Scale, which provides a quantitative measure of autistic-like behavior, primarily focused on social relatedness....

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Source

Identifiers

PMID: 17403980
DOI: 10.1176/ajp.2007.164.4.656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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