Article
Mitochondrial translation initiation factor 3 polymorphism and Parkinson's disease.
Neuroscience letters - 17 Dec 2010
Behrouz Bahareh, Vilariño-Güell Carles, Heckman Michael G, Soto-Ortolaza Alexandra I, Aasly Jan O, Sando Sigrid, Lynch Timothy, Craig David, Uitti Ryan J, Wszolek Zbigniew K, Ross Owen A, Farrer Matthew J
Abstract excerpt
Mitochondrial dysfunction has been proposed to play a role in the pathogenesis of Parkinson's disease (PD). Supportive of this hypothesis, several genetic variants that regulate mitochondrial function and homeostasis have been described to alter PD susceptibility. A recent report demonstrated association of a single nucleotide polymorphism in the mitochondrial translation initiation factor 3 (MTIF3) gene with PD...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
