Article
Association of the COQ2 V393A Variant with Parkinson's Disease: A Case-Control Study and Meta-Analysis.
PloS one - 1 Jan 2015
Yang Xinglong, Xi Jing, Zhao Quanzhen, Jia Hua, An Ran, Liu Zhuolin, Xu Yanming
Abstract excerpt
Both Parkinson's disease (PD) and multiple system atrophy (MSA) are neurodegenerative diseases of uncertain etiology, but they show similarities in their pathology and clinical course. The fact that the gene encoding α-synuclein is associated with both diseases also suggests that they share some genetic determinants. Recent studies in Japan associating MSA with a variant in the COQ2 gene led us to question...
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