A genomewide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12.

doi:10.1002/ajmg.b.31127

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Article

A genomewide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2010

Butler Amy W, Breen Gerome, Tozzi Federica, Craddock Nick, Gill Mike, Korszun Ania, Maier Wolfgang, Middleton Lefkos T, Mors Ole, Owen Michael J, Perry Julia, Preisig Martin, Rice John P, Rietschel Marcella, Jones Lisa, Farmer Anne E, Lewis Cathryn M, McGuffin Peter

Abstract excerpt

Suicidal behavior is commonly associated with depression. Twin studies indicate that both suicidality and major depressive disorder (MDD) are heritable. However, epidemiological evidence suggests that the inheritance of suicidality is likely to be independent of the underlying psychiatric disorder, implying a distinct genetic contribution to suicidality. We conducted a genomewide linkage search aiming to detect...

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PMID: 20886545
DOI: 10.1002/ajmg.b.31127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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