Article
Attempted suicide in bipolar disorder pedigrees: evidence for linkage to 2p12.
Biological psychiatry - 1 Mar 2007
Willour Virginia L, Zandi Peter P, Badner Judith A, Steele Jo, Miao Kuangyi, Lopez Victor, MacKinnon Dean F, Mondimore Francis M, Schweizer Barbara, McInnis Melvin G, Miller Erin B, Depaulo J Raymond, Gershon Elliot S, McMahon Francis J, Potash James B
Abstract excerpt
BACKGROUND: We are interested in identifying susceptibility genes that predispose subjects to attempted suicide. METHODS: We conducted a secondary analysis of genome-wide linkage data from 162 bipolar pedigrees that incorporated attempted suicide as a clinical covariate. RESULTS: The strongest covariate-based linkage signal was seen on 2p12 at marker D2S1777. The logarithm of odds (LOD) score at marker D2S1777...
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