Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Basic Fibroblast Growth Factor Activates MEK/ERK Cell Signaling Pathway and Stimulates the Proliferation of Chicken Primordial Germ Cells

23 Sept 2010

Abstract excerpt

BACKGROUND: Long-term maintenance of avian primordial germ cells (PGCs) in vitro has tremendous potential because it can be used to deepen our understanding of the biology of PGCs. A transgenic bioreactor based on the unique migration of PGCs toward the recipients' sex cord via the bloodstream and thereby creating a germline chimeric bird has many potential applications. However, the growth factors and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Pluripotent Stem Cells Research
Share to Xenotransplantation and immune response

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20886037
DOI: 10.1371/journal.pone.0012968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Basic Fibroblast Growth Factor Activates MEK/ERK Cell Signaling Pathway and Stimulates the Proliferation of Chicken Primordial Germ CellsPMID 20886037Read ↗

Characterisation and Germline Transmission of Cultured Avian Primordial Germ CellsSemantic proximity Read ↗

Long term-cultured and cryopreserved primordial germ cells from various chicken breeds retain high proliferative potential and gonadal colonisation competency.Semantic proximity Read ↗

Short-term gonadal cultures are sufficient for germline transmission in a songbirdSemantic proximity Read ↗

Transcriptome comparison between the cultured and in vivo Chick Primordial Germ Cells by SMART-seq-based single cell RNA sequencingSemantic proximity Read ↗

Growth factors sustain primordial germ cell survival, proliferation and entering into meiosis in the absence of somatic cellsSemantic proximity Read ↗

Feeder‐independent canine induced pluripotent stem cells maintained under serum‐free conditionsSemantic proximity Read ↗

Conserved Role of bFGF and a Divergent Role of LIF for Pluripotency Maintenance and Survival in Canine Pluripotent Stem CellsSemantic proximity Read ↗

Regulation of primordial germ cell development in the mouseSemantic proximity Read ↗

Fibroblast growth factor-binding protein facilitates the growth and migration of skin-derived precursors.Semantic proximity Read ↗

Long-Term Rock Dove ( <i>Columba livia</i> ) Primordial Germ Cell Culture: A Tool for Avian ConservationSemantic proximity Read ↗

Dose-dependent functions of fibroblast growth factor 9 regulate the fate of murine XY primordial germ cells†Semantic proximity Read ↗

The majority of early primordial germ cells acquire pluripotency by AKT activation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.