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Feeder‐independent canine induced pluripotent stem cells maintained under serum‐free conditions

27 Feb 2017

Abstract excerpt

Canine induced pluripotent stem cells (ciPSCs) are an attractive source for regenerative veterinary medicine, and may also serve as a disease model for human regenerative medicine. Extending the application of ciPSCs from bench to bedside, however, requires resolving many issues. We generated ciPSCs expressing doxycycline-inducible murine Oct3/4 (Pou5f1), Sox2, Klf4, and c-Myc, which were introduced using...

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PMID: 28240438
DOI: 10.1002/mrd.22789

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