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Article

Of Mice, Not Men: No Evidence for Graft-versus-Host Disease in Humans Receiving T-Cell Receptor–Transduced Autologous T Cells

1 Oct 2010

Abstract excerpt

A recent article by Bendle et al.1Bendle GM Linnemann C Hooijkaas AI Bies L de Witte MA Jorritsma A et al.Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.Nat Med. 2010; 16: 565-570Crossref PubMed Scopus (329) Google Scholar reported a high incidence of lethal graft-versus-host disease (GVHD) in mice receiving a lymphodepleting regimen followed by syngeneic cells transduced with...

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Identifiers

PMID: 20885433
DOI: 10.1038/mt.2010.195

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