Article
Analysis of hOGG1 genotype as a prognostic marker for muscle invasive bladder cancer: a novel approach using peptide nucleic acid-mediated, real-time PCR clamping.
Urologic oncology - 1 Sept 2012
Kim Eun-Jung, Yan Chunri, Ha Yun-Sok, Jeong Pildu, Yi Kim Isaac, Moon Sung-Kwon, Choi Yung Hyun, Kim Wun-Jae
Abstract excerpt
OBJECTIVE: DNA damage repair mechanisms are a source of genetic mutation and are believed to play an important role in human cancer. Human 8-oxoguanine DNA glycosylase 1 (hOGG1) is involved in the recognition and repair of DNA damage. The value of the hOGG1 genotype as a prognostic indicator for bladder cancer (BC) was assessed using a novel technological approach. MATERIALS AND METHODS: The association between...
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