Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase.

Phlebology - 1 Jun 2011

Wilmanns C, Casey A, Schinzel H, Walter P K

Abstract excerpt

BACKGROUND: The purpose of this study was to compare the genetic background of superficial (SVT) and deep vein thrombosis (DVT). METHODS: Factor V (FV)-Leiden (G16891A)-, factor II(G20210A)-mutations, protein C- and S, as well as methylenetetrahydrofolate reductase (MTHFR) polymorphisms at C677T and A1298C, and serum homocysteine levels (hcy) were determined in 29 patients with SVT and 26 with DVT. Findings FV-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Factor V
Share to Homocysteine
Share to Methylenetetrahydrofolate Dehydrogenase (NADP)

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation, Missense

Share to Prothrombin

Share to Thrombophlebitis

Share to Varicose Veins

Share to Venous Thrombosis

Source

Identifiers

PMID: 20881312
DOI: 10.1258/phleb.2009.009075

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Superficial thrombophlebitis in varicose vein disease: the particular role of methylenetetrahydrofolate reductase.PMID 20881312Read ↗

Superficial venous thrombosis: prevalence of common genetic risk factors and their role on spreading to deep veins.Semantic proximity Read ↗

Genetic risk factors for superficial vein thrombosis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene C677T mutation and plasma homocysteine level in Behçet's disease.Semantic proximity Read ↗

[Study on the association of polymorphisms in homocysteine metabolism related enzymes with deep venous thrombosis].Semantic proximity Read ↗

A second mutation in the methylenetetrahydrofolate reductase gene and the risk of venous thrombotic disease.Semantic proximity Read ↗

[A common mutation C677T in the 5,10-methyltetrahydrofolate reductase gene is associated to idiopathic deep venous thrombosis].Semantic proximity Read ↗

Hyperhomocysteinemia and the compound heterozygous state for methylene tetrahydrofolate reductase are independent risk factors for deep vein thrombosis among South Indians.Semantic proximity Read ↗

Effects of factor V gene G1691A, methylenetetrahydrofolate reductase gene C677T, and prothombin gene G20210A mutations on deep venous thrombogenesis in Behçet's disease.Semantic proximity Read ↗

The prevalence of hyperhomocysteinemia, methylene tetrahydrofolate reductase C677T mutation, and vitamin B12 and folate deficiency in patients with chronic venous insufficiency.Semantic proximity Read ↗

Common C677T polymorphism in the methylenetetrahydrofolate reductase gene increases the risk for deep vein thrombosis in patients with predisposition of thrombophilia.Semantic proximity Read ↗

An Unexpectedly High Rate of Thrombophilia Disorders in Patients with Superficial Vein Thrombosis of the Lower Extremities.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase TT677 genotype is associated with venous thrombosis independently of the coexistence of the FV Leiden and the prothrombin A20210 mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.