Article
The prevalence of hyperhomocysteinemia, methylene tetrahydrofolate reductase C677T mutation, and vitamin B12 and folate deficiency in patients with chronic venous insufficiency.
Journal of vascular surgery - 1 Nov 2003
Sam Rachel C, Burns Paul J, Hobbs Simon D, Marshall Tim, Wilmink Antonius B M, Silverman Stanley H, Bradbury Andrew W
Abstract excerpt
INTRODUCTION: Hyperhomocysteinemia (HHcy) is a risk factor for venous thromboembolism, which in turn is a major cause of chronic venous insufficiency. HHcy may be more common in patients with chronic venous insufficiency, but the cause is unknown. METHODS: One hundred hospital outpatients (52 women; median age, 66.5 years [interquartile range, 53-77 years] with venous disease C(2-6) underwent assessment of serum...
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