Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of the Glucocorticoid and Mineralocorticoid Receptors in Skin Pathophysiology

29 Jun 2018

Abstract excerpt

The nuclear hormone receptor (NR) superfamily comprises approximately 50 evolutionarily conserved proteins that play major roles in gene regulation by prototypically acting as ligand-dependent transcription factors. Besides their central role in physiology, NRs have been largely used as therapeutic drug targets in many chronic inflammatory conditions and derivatives of their specific ligands, alone or in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatology and Skin Diseases
Share to Estrogen and related hormone effects
Share to Urticaria and Related Conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29966221
DOI: 10.3390/ijms19071906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of the Glucocorticoid and Mineralocorticoid Receptors in Skin PathophysiologyPMID 29966221Read ↗

Glucocorticoid receptors, epidermal homeostasis and hair follicle differentiationSemantic proximity Read ↗

Epidermal glucocorticoid and mineralocorticoid receptors act cooperatively to regulate epidermal development and counteract skin inflammation.Semantic proximity Read ↗

The mineralocorticoid receptor modulates timing and location of genomic binding by glucocorticoid receptor in response to synthetic glucocorticoids in keratinocytesSemantic proximity Read ↗

Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid ReceptorSemantic proximity Read ↗

Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytesSemantic proximity Read ↗

Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal DifferentiationSemantic proximity Read ↗

The Glucocorticoid Receptor: Isoforms, Functions, and Contribution to Glucocorticoid SensitivitySemantic proximity Read ↗

The Human Glucocorticoid Receptor Beta: From Molecular Mechanisms to Clinical ImplicationsSemantic proximity Read ↗

Glucocorticoid receptors: finding the middle groundSemantic proximity Read ↗

Glucocorticoid Receptor Regulates Overlapping and Differential Gene Subsets in Developing and Adult SkinSemantic proximity Read ↗

Novel Mechanism of Steroid Action in Skin through Glucocorticoid Receptor MonomersSemantic proximity Read ↗

Zebrafish Mutant Lines Reveal the Interplay between nr3c1 and nr3c2 in the GC-Dependent Regulation of Gene TranscriptionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.