Article
Gender influences cardiac function in the mdx model of Duchenne cardiomyopathy.
Muscle & nerve - 1 Oct 2010
Bostick Brian, Yue Yongping, Duan Dongsheng
Abstract excerpt
Aged mdx mice represent an important model for studying Duchenne cardiomyopathy. Herein we compared the cardiac phenotypes of 22-month-old male and female mdx mice. Surprisingly, only females displayed the characteristic cardiac dilation on pressure-volume loop analysis. Female mdx mice also exhi...
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