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Article

Common polymorphisms in GSTM1, GSTT1, GSTP1, GSTA1 and susceptibility to colorectal cancer in the Central European population.

European journal of medical research - 14 Jun 2012

Hezova Renata, Bienertova-Vasku Julie, Sachlova Milana, Brezkova Veronika, Vasku Anna, Svoboda Marek, Radová Lenka, Kiss Igor, Vyzula Rostislav, Slaby Ondrej

Abstract excerpt

BACKGROUND: Central Europe presents with the highest incidence of sporadic colorectal cancer (CRC) worldwide. As sporadic CRC represents a typical multifactorial disease, it is characterized by intense interaction of the genetic background with the environment. Glutathione S-transferases could act as attractive susceptibility genes for CRC, as they are directly involved in conjugation between glutathione and...

Topics

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Colorectal Neoplasms
Czech Republic
Disease Susceptibility
Gene-Environment Interaction
Glutathione S-Transferase pi

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glutathione Transferase

Real-Time Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 22697302
DOI: 10.1186/2047-783X-17-17
PMCID: PMC3480935

Genes

GSTP1
GSTA1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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