Article
Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction.
Circulation. Cardiovascular genetics - 1 Oct 2010
Shah Tina, Newcombe Paul, Smeeth Liam, Addo Juliet, Casas Juan P, Whittaker John, Miller Michelle A, Tinworth Lorna, Jeffery Steve, Strazzullo Pasquale, Cappuccio Francesco P, Hingorani Aroon D
Abstract excerpt
BACKGROUND: Eligibility for rosuvastatin treatment for cardiovascular disease prevention includes a C-reactive protein (CRP) concentration >2 mg/L. Most observational studies of CRP and cardiovascular disease have been in Europeans. We evaluated the influence of ancestry on population CRP concentration to assess the implications for statin targeting in non-Europeans. METHODS AND RESULTS: In a systematic review...
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