Article
RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype.
Cancer research - 15 Oct 2010
Yang Dazhi, Kedei Noemi, Li Luowei, Tao Juan, Velasquez Julia F, Michalowski Aleksandra M, Tóth Balázs I, Marincsák Rita, Varga Attila, Bíró Tamás, Yuspa Stuart H, Blumberg Peter M
Abstract excerpt
RasGRP3 mediates the activation of the Ras signaling pathway that is present in many human cancers. Here, we explored the involvement of RasGRP3 in the formation and maintenance of the prostate cancer phenotype. RasGRP3 expression was elevated in multiple human prostate tumor tissue samples and i...
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