Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SLOPE: a quick and accurate method for locating non-SNP structural variation from targeted next-generation sequence data.

Bioinformatics (Oxford, England) - 1 Nov 2010

Abel Haley J, Duncavage Eric J, Becker Nils, Armstrong Jon R, Magrini Vincent J, Pfeifer John D

Abstract excerpt

MOTIVATION: Targeted 'deep' sequencing of specific genes or regions is of great interest in clinical cancer diagnostics where some sequence variants, particularly translocations and indels, have known prognostic or diagnostic significance. In this setting, it is unnecessary to sequence an entire...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome
Share to Polymorphism, Single Nucleotide
Share to Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Software

Share to Translocation, Genetic

Source

Identifiers

PMID: 20876606
DOI: 10.1093/bioinformatics/btq528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20876606-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SLOPE: a quick and accurate method for locating non-SNP structural variation from targeted next-generation sequence data.PMID 20876606Read ↗

BreakDancer: an algorithm for high-resolution mapping of genomic structural variation.Semantic proximity Read ↗

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers.Semantic proximity Read ↗

SvABA: Genome-wide detection of structural variants and indels by local assemblySemantic proximity Read ↗

FocalSV: target region-based structural variant assembly and refinement using single-molecule long read sequencing dataSemantic proximity Read ↗

PerSVade: Personalized Structural Variation detection in your species of interestSemantic proximity Read ↗

Tangram: a comprehensive toolbox for mobile element insertion detection.Semantic proximity Read ↗

ReALLEN: structural variation discovery in cancer genome by sensitive analysis of single-end readsSemantic proximity Read ↗

Precise characterization of somatic complex structural variations from paired long-read sequencing data with nanomonsvSemantic proximity Read ↗

Robust and exact structural variation detection with paired-end and soft-clipped alignments: SoftSV compared with eight algorithms.Semantic proximity Read ↗

FirstSV: Fast and Accurate Approach of Structural Variations Detection for Short DNA fragmentsSemantic proximity Read ↗

MetaSV: an accurate and integrative structural-variant caller for next generation sequencing.Semantic proximity Read ↗

Severus: accurate detection and characterization of somatic structural variation in tumor genomes using long readsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.