Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Saccharomyces cerevisiae coq10 null mutants are responsive to antimycin A.

The FEBS journal - 1 Nov 2010

Busso Cleverson, Tahara Erich B, Ogusucu Renata, Augusto Ohara, Ferreira-Junior Jose Ribamar, Tzagoloff Alexander, Kowaltowski Alicia J, Barros Mario H

Abstract excerpt

Deletion of COQ10 in Saccharomyces cerevisiae elicits a respiratory defect characterized by the absence of cytochrome c reduction, which is correctable by the addition of exogenous diffusible coenzyme Q(2). Unlike other coq mutants with hampered coenzyme Q(6) (Q(6) ) synthesis, coq10 mutants have near wild-type concentrations of Q(6). In the present study, we used Q-cycle inhibitors of the coenzyme...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimycin A
Share to Aspergillus fumigatus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome c Group

Share to Electron Spin Resonance Spectroscopy

Share to Oxygen Consumption

Share to Superoxides

Share to Thiazoles

Share to Ubiquinone

Source

Open in PubMed Open full text

Identifiers

PMID: 20875086
DOI: 10.1111/j.1742-4658.2010.07862.x
PMCID: PMC3155804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Saccharomyces cerevisiae coq10 null mutants are responsive to antimycin A.PMID 20875086Read ↗

Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyces pombe.Semantic proximity Read ↗

Uptake of exogenous coenzyme Q and transport to mitochondria is required for bc1 complex stability in yeast coq mutants.Semantic proximity Read ↗

The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration.Semantic proximity Read ↗

Nonfunctional coq10 mutants maintain the ERMES complex and reveal true phenotypes associated with the loss of the coenzyme Q chaperone protein Coq10.Semantic proximity Read ↗

Coenzyme Q10 deficiencies: pathways in yeast and humans.Semantic proximity Read ↗

Overexpression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the coenzyme Q6 biosynthetic pathway.Semantic proximity Read ↗

Inaccurately assembled cytochrome c oxidase can lead to oxidative stress-induced growth arrest.Semantic proximity Read ↗

Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency.Semantic proximity Read ↗

The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.Semantic proximity Read ↗

Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity.Semantic proximity Read ↗

A defect in coenzyme Q biosynthesis is responsible for the respiratory deficiency in Saccharomyces cerevisiae abc1 mutants.Semantic proximity Read ↗

Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.