Article
Mutations in EGFR signal pathway in correlation with response to treatment of head and neck cancers.
The Gulf journal of oncology - 1 Jul 2011
Neuwirthová J, Pavel S, Rottenberg J, Kostřica R, Zdeněk M, Hajdúch M, Drábek J, Srovnal J, Berkovcová J
Abstract excerpt
UNLABELLED: The prognostic and predictive value of the epidermal growth factor receptor (EGFR) expression and some genetic alterations in an EGFR signal pathway, such as the EGFR amplification, the EGFR activating tyrosine kinase domain mutations or the k-ras gene mutation were investigated in our study. The aim of the research was to evaluate the occurrence of the above-mentioned biomarkers in correlation with a...
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