Article
MicroRNAs: tiny targets for engineering CHO cell phenotypes?
Biotechnology letters - 1 Jan 2011
Barron Niall, Sanchez Noelia, Kelly Paul, Clynes Martin
Abstract excerpt
The ability of microRNAs to influence gene expression is now recognized as a fundamental layer of regulation within the cell. MicroRNAs have a major impact on most biological processes and have generated considerable interest as potential biomarkers as well as therapeutic or engineering targets. In this review we provide a brief overview of their biogenesis, genomic organization and mode of action, followed by a...
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