Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease

1 Jan 2010

Abstract excerpt

Since their initial generation in the mid 1990s, transgenic mouse models of Alzheimers's disease (AD) have been proven to be valuable model systems which are indispensable for modern AD research. Whereas most of these models are characterized by extensive amyloid plaque pathology, inflammatory changes and often behavioral deficits, modeling of neuron loss was much less successful. The present paper discusses the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Computational Drug Discovery Methods
Share to Nuclear Receptors and Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20871861
DOI: 10.4061/2010/723782

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuron Loss in Transgenic Mouse Models of Alzheimer's DiseasePMID 20871861Read ↗

Insights into Alzheimer disease pathogenesis from studies in transgenic animal models.Semantic proximity Read ↗

Transgenic Mouse Models of Alzheimer Disease: Developing a Better Model as a Tool for Therapeutic InterventionsSemantic proximity Read ↗

Overview of Transgenic Mouse Models for Alzheimer's DiseaseSemantic proximity Read ↗

Transgenic Mouse Models of Alzheimer’s Disease: An Integrative AnalysisSemantic proximity Read ↗

Mouse Models of Alzheimer’s DiseaseSemantic proximity Read ↗

Animal and Cellular Models of Alzheimer’s Disease: Progress, Promise, and Future ApproachesSemantic proximity Read ↗

Insights on the Use of Transgenic Mice Models in Alzheimer’s Disease ResearchSemantic proximity Read ↗

Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's DiseaseSemantic proximity Read ↗

Transgenic mouse models of Alzheimer's disease.Semantic proximity Read ↗

Neuron loss in APP transgenic miceSemantic proximity Read ↗

Transgenic mice expressing Alzheimer amyloid precursor proteins.Semantic proximity Read ↗

Transgenic mouse models of Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.