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Article

Polymorphisms in promoter sequences of the p15 ( INK4B ) and PTEN genes of normal Japanese individuals.

Biochemical genetics - 1 Dec 2010

Ohsaka Yasuhito, Yogosawa Shingo, Nakanishi Ryoko, Sakai Toshiyuki, Nishino Hoyoku

Abstract excerpt

Gene promoter regions of p15(INK4B), a cyclin-dependent kinase inhibitor, and phosphatase and tensin homolog (PTEN), a dual-function protein and lipid phosphatase, interact with regulatory factors for gene transcription and methylation. Normal individuals exhibit sequence polymorphisms in these regulatory genes. We isolated genomic DNA from whole blood of healthy Japanese individuals and sequenced promoter...

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Source

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PMID: 20862607
DOI: 10.1007/s10528-010-9379-3

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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