Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/Beta Interferon

Abstract excerpt

Production of alpha/beta interferons (IFN-alpha/beta) in response to viral infection is one of the main defense mechanisms of the innate immune system. Many viruses therefore encode factors that subvert the IFN system to enhance their virulence. Bunyamwera virus (BUN) is the prototype of the Bunyaviridae family. By using reverse genetics, we previously produced a recombinant virus lacking the nonstructural...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mosquito-borne diseases and control
• Share to Vector-Borne Animal Diseases
• Share to Viral Infections and Vectors