Safety and Immunogenicity of a Single Administration of Live-attenuated Japanese Encephalitis Vaccine in Previously Primed 2- to 5-year-olds and Naive 12- to 24-month-olds

Abstract excerpt

BACKGROUND: Safe and effective Japanese encephalitis (JE) vaccines are needed to protect populations living in or visiting endemic areas. A live-attenuated JE-chimeric virus vaccine (JE-CV) has been developed with a single-dose regimen. METHODS: In an open-label, crossover study, 100 children aged 2 to 5 years with a history of 2-dose primary vaccination with mouse-brain derived inactivated JE vaccine according...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hepatitis Viruses Studies and Epidemiology
• Share to Mosquito-borne diseases and control
• Share to Viral Infections and Outbreaks Research