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Article

Immune response to live-attenuated Japanese encephalitis vaccine (JE-CV) neutralizes Japanese encephalitis virus isolates from south-east Asia and India.

BMC infectious diseases - 21 Mar 2014

Bonaparte Matthew, Dweik Bashir, Feroldi Emmanuel, Meric Claude, Bouckenooghe Alain, Hildreth Stephen, Hu Branda, Yoksan Sutee, Boaz Mark

Abstract excerpt

BACKGROUND: During clinical development of the licensed Japanese encephalitis chimeric virus vaccine (JE-CV), the neutralization capacity of vaccine-induced antibodies was assessed against the vaccine virus and against well characterized wild-type (wt) viruses isolated between 1949-1991. We assessed whether JE-CV-induced antibodies can also neutralize more recent wt Japanese encephalitis virus (JEV) isolates...

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Identifiers

PMID: 24656175
DOI: 10.1186/1471-2334-14-156
PMCID: PMC3994458

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