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Article

Genetic association of immunosenescence to immune decline.

Immunogenetics - 28 Jul 2026

Alshahrani Mohammad Y, AlKhafaje Zahraa, Hussein Uday Abdul-Reda, Adel Zahraa, Alkadir Ola Kamal A, Aldulaimi Ahmed, Jameel Rafid Kamal, Albadr Rafid Jihad, Alwan Mariem, Smerat Aseel

Abstract excerpt

Immunosenescence is a complex biological process characterized by progressive remodeling of immune function during aging, leading to increased susceptibility to infections, chronic inflammatory diseases, cancer, and reduced vaccine efficacy. While cumulative antigen exposure, infections, lifestyle factors, environmental exposures, and epigenetic influences contribute to immune decline, a growing body of evidence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42517957
DOI: 10.1007/s00251-026-01409-y

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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