Article
HIV-1 diversity after a class switch failure.
AIDS research and human retroviruses - 1 Nov 2010
Kolber Michael A, Buendia Patricia, Degruttola Victor, Moore Richard D
Abstract excerpt
The purpose of this study is to evaluate whether the choice of a PI- or an efavirenz (EFV)-based HAART initial regimen impacts on the viral diversity after failure from a second, class-switch salvage regimen. Sequential HAART failures after a class switch were identified for which the genotypes showed evidence of signature mutations at each failure. Each second failure was required to be from a viral burden...
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