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Microvesicle Induction of Prostate Specific Gene Expression in Normal Human Bone Marrow Cells

19 Sept 2010

Abstract excerpt

PURPOSE: Transfer of genetic material from cancer cells to normal cells occurs via microvesicles. Cell specific phenotypes can be induced in normal cells by the transfer of material in microvesicles, leading to genetic changes. We report the identification and expression of prostate specific genes in normal human marrow cells co-cultured with human prostate cancer cells. MATERIALS AND METHODS: We harvested...

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PMID: 20850816
DOI: 10.1016/j.juro.2010.06.119

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