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Article

The dynamic stem cell microenvironment is orchestrated by microvesicle-mediated transfer of genetic information.

1 Mar 2010

Abstract excerpt

It has been commonly supposed that adult stem cells co-localize with supporting cells within specific regions or specialized microenvironment in each tissue/organ, called stem cell niche. This concept was based on the assumption that stem cells are intrinsically hierarchical in nature. However, recent data indicate that stem cells may represent a continuum with reversible alterations in phenotype taking place...

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PMID: 20054810
DOI: 10.14670/hh-25.397

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