Article
Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification.
Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2010
Shen Haiqing, Bielak Lawrence F, Ferguson Jane F, Streeten Elizabeth A, Yerges-Armstrong Laura M, Liu Jie, Post Wendy, O'Connell Jeffery R, Hixson James E, Kardia Sharon L R, Sun Yan V, Jhun Min A, Wang Xuexia, Mehta Nehal N, Li Mingyao, Koller Daniel L, Hakonarson Hakan, Keating Brendan J, Rader Daniel J, Shuldiner Alan R, Peyser Patricia A, Reilly Muredach P, Mitchell Braxton D
Abstract excerpt
OBJECTIVE: The vitamin D endocrine system is essential for calcium homeostasis, and low levels of vitamin D metabolites have been associated with cardiovascular disease risk. We hypothesized that DNA sequence variation in genes regulating vitamin D metabolism and signaling pathways might influenc...
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