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Article

The relationship between diastolic blood pressure and coronary artery calcification is dependent on single nucleotide polymorphisms on chromosome 9p21.3.

BMC medical genetics - 4 Sept 2014

Kim Daniel S, Smith Jennifer A, Bielak Lawrence F, Wu Chun-Yi, Sun Yan V, Sheedy Patrick F, Turner Stephen T, Peyser Patricia A, Kardia Sharon L R

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) within the 9p21.3 genomic region have been consistently associated with coronary heart disease (CHD), myocardial infarction, and quantity of coronary artery calcification (CAC), a marker of subclinical atherosclerosis. Prior studies have established an association between blood pressure measures and CAC. To examine mechanisms by which the 9p21.3 genomic region...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25185447
DOI: 10.1186/s12881-014-0089-2
PMCID: PMC4168694

Genes

DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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