Article
[Uracil, contained in DNA, can direct the correction of mispaired nucleotides in human cells].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Dec 1990
Golubovskaia V M, Aprelikova O N, Tomilin N V
Abstract excerpt
The mismatch correction has been studied in human cells and presented in this paper. In the study the experimental model with half-containing hetroduplex (-1 residue in the polylinker region of lac gene) M13 DNA has been used. M 13 DNA was isolated from human cells 24 hours after transfection and transformed into ung+ and ung- cells of Escherichia coli. The percentage of lac- colonies (formed due to frameshift...
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