Article
Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance.
Nature - 16 Sept 2010
Kim Hye-Jung, Verbinnen Bert, Tang Xiaolei, Lu Linrong, Cantor Harvey
Abstract excerpt
The ability to produce vigorous immune responses that spare self tissues and organs depends on the elimination of autoreactive T and B cells. However, purging of immature and mature self-reactive T and B cells is incomplete and may also require the involvement of cells programmed to suppress immu...
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