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SIRT1 Is a Novel Regulator of Key Pathways of Human Labor1

16 Sept 2010

Abstract excerpt

Human sirtuin (SIRT) 1 and SIRT2, which possess nicotinamide adenosine dinucleotide (NAD(+))-dependent deacetylase activity, exhibit anti-inflammatory actions. However, there are no data available on SIRT1 and SIRT2 expression and regulation in human intrauterine tissues. Thus, the aim of this study was to characterize the localization and expression of SIRT1 and SIRT2 in 1) placenta and fetal membranes before...

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PMID: 20844277
DOI: 10.1095/biolreprod.110.086983

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