Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SIRT6 Is Decreased with Preterm Labor and Regulates Key Terminal Effector Pathways of Human Labor in Fetal Membranes1

8 Nov 2012

Abstract excerpt

Preterm birth is a major determinant of neonatal mortality and morbidity, affecting approximately one-third of preterm births as a result of prelabor rupturing of membranes. Infection and inflammation have strong causal links to preterm delivery, resulting in the activation of nuclear factor-kappaB (NFKB) and its downstream targets. Human sirtuin (SIRT) 6, which has ADP-ribosyl transferase and deacetylase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fatty Acid Research and Health
Share to Pregnancy-related medical research
Share to Preterm Birth and Chorioamnionitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23136298
DOI: 10.1095/biolreprod.112.105163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SIRT6 Is Decreased with Preterm Labor and Regulates Key Terminal Effector Pathways of Human Labor in Fetal Membranes1PMID 23136298Read ↗

SIRT1 Is a Novel Regulator of Key Pathways of Human Labor1Semantic proximity Read ↗

Sirtuins: Subtle Regulators Involved in Convoluted Mechanisms of PregnancySemantic proximity Read ↗

Transcriptomic Profiling of Human Choriodecidua During Term Labor: Inflammation as a Key Driver of LaborSemantic proximity Read ↗

Is human labor at term an inflammatory condition?Semantic proximity Read ↗

Characteristic Changes in Decidual Gene Expression Signature in Spontaneous Term ParturitionSemantic proximity Read ↗

Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at termSemantic proximity Read ↗

ATF3 is a negative regulator of inflammation in human fetal membranesSemantic proximity Read ↗

The Placental NLRP3 Inflammasome and Its Downstream Targets, Caspase-1 and Interleukin-6, Are Increased in Human Fetal Growth Restriction: Implications for Aberrant Inflammation-Induced Trophoblast DysfunctionSemantic proximity Read ↗

Diverse actions of sirtuin-1 on ovulatory genes and cell death pathways in human granulosa cellsSemantic proximity Read ↗

Modeling hormonal and inflammatory contributions to preterm and term labor using uterine temporal transcriptomicsSemantic proximity Read ↗

N-Myc Down-regulated Gene 1 Modulates the Response of Term Human Trophoblasts to Hypoxic InjurySemantic proximity Read ↗

Initiation of human parturition: signaling from senescent fetal tissues via extracellular vesicle mediated paracrine mechanismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.