Article
Stimulation of human dendritic cells by wild-type and M protein mutant vesicular stomatitis viruses engineered to express bacterial flagellin.
Journal of virology - 1 Nov 2010
Ahmed Maryam, Puckett Shelby, Arimilli Subhashini, Braxton Cassandra L, Mizel Steven B, Lyles Douglas S
Abstract excerpt
Vesicular stomatitis viruses (VSVs) containing wild-type (wt) or mutant matrix (M) proteins are being developed as candidate vaccine vectors due to their ability to induce innate and adaptive immunity. Viruses with wt M protein, such as recombinant wild-type (rwt) virus, stimulate maturation of d...
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