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Article

Immune response in the absence of neurovirulence in mice infected with m protein mutant vesicular stomatitis virus.

Journal of virology - 1 Sept 2008

Ahmed Maryam, Marino Tracie R, Puckett Shelby, Kock Nancy D, Lyles Douglas S

Abstract excerpt

Matrix (M) protein mutants of vesicular stomatitis virus (VSV), such as rM51R-M virus, are less virulent than wild-type (wt) VSV strains due to their inability to suppress innate immunity. Studies presented here show that when inoculated intranasally into mice, rM51R-M virus was cleared from nasal mucosa by day 2 postinfection and was attenuated for spread to the central nervous system, in contrast to wt VSV,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18614644
DOI: 10.1128/JVI.00915-08
PMCID: PMC2546904

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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