Article
MRE11 expression is predictive of cause-specific survival following radical radiotherapy for muscle-invasive bladder cancer.
Cancer research - 15 Sept 2010
Choudhury Ananya, Nelson Louisa D, Teo Mark T W, Chilka Sameer, Bhattarai Selina, Johnston Colin F, Elliott Faye, Lowery Johanna, Taylor Claire F, Churchman Michael, Bentley Johanne, Knowles Margaret A, Harnden Patricia, Bristow Robert G, Bishop D Timothy, Kiltie Anne E
Abstract excerpt
Radical radiotherapy and surgery achieve similar cure rates in muscle-invasive bladder cancer, but the choice of which treatment would be most beneficial cannot currently be predicted for individual patients. The primary aim of this study was to assess whether expression of any of a panel of DNA damage signaling proteins in tumor samples taken before irradiation could be used as a predictive marker of...
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