Article
Genetic Polymorphisms in miR-146a, miR-196a2 and miR-125a Genes and its Association in Prostate Cancer.
Pathology oncology research : POR - 1 Jan 2020
Damodaran Mohan, Paul Solomon F D, Venkatesan Vettriselvi
Abstract excerpt
The increase in incidence of prostate cancer in the Indian Population stresses the need to identify genetic markers for susceptibility and prognosis. Recent studies show that microRNAs play an important role in tumorigenesis by altering proliferation, differentiation and cell death. Gene polymorphisms not only in promoter region but also within miRNA gene have been shown to affect expression. The present study...
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