Over-presentation of apolipoprotein E gene variants E3/E4 and cardiovascular disease risk factors among Ghanaian breast cancer patients.

doi:10.1186/s12885-026-16354-y

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Article

Over-presentation of apolipoprotein E gene variants E3/E4 and cardiovascular disease risk factors among Ghanaian breast cancer patients.

BMC cancer - 23 Jun 2026

Antonio Daniel Nii Martey, Annani-Akollor Max, Fondjo Linda Ahenkorah, Anang-Quartey Yvonne, Owusu Hubert, Arko-Boham Benjamin, Santa Sheila, Quaye Osbourne, Tagoe Emmanuel Ayitey

Abstract excerpt

BACKGROUND: Apolipoprotein E (APO E), a member of the apolipoprotein family, plays a crucial role in lipid metabolism. The association between dyslipidaemia and breast cancer remains inconclusive, and the relationship between APO E gene variants and breast cancer is not well established. This study aimed to determine the distribution of APO E gene variants and assess dyslipidaemia as cardiovascular disease risk...

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Topics

Humans
Female
Breast Neoplasms
Ghana
Middle Aged
Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Case-Control Studies

Adult

Risk Factors

Genetic Predisposition to Disease

Apolipoprotein E4

Heart Disease Risk Factors

Apolipoprotein E3

Apolipoproteins E

Dyslipidemias

Aged

Lipids

Source

Open in PubMed

Identifiers

PMID: 42337705
DOI: 10.1186/s12885-026-16354-y

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