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Article

Optimal strategies for sequential validation of significant features from high-dimensional genomic data.

Journal of toxicology and environmental health. Part A - 1 Jan 2012

Lohr Miriam, Köllmann Claudia, Freis Evgenia, Hellwig Birte, Hengstler Jan G, Ickstadt Katja, Rahnenführer Jörg

Abstract excerpt

High-dimensional genomic studies play a key role in identifying critical features that are significantly associated with a phenotypic outcome. The two most important examples are the detection of (1) differentially expressed genes from genome-wide gene expression studies and (2) single-nucleotide...

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PMID: 22686304
DOI: 10.1080/15287394.2012.674912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22686304-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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