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Article

Impairment of circulating endothelial progenitors in Down syndrome.

BMC medical genomics - 13 Sept 2010

Costa Valerio, Sommese Linda, Casamassimi Amelia, Colicchio Roberta, Angelini Claudia, Marchesano Valentina, Milone Lara, Farzati Bartolomeo, Giovane Alfonso, Fiorito Carmela, Rienzo Monica, Picardi Marco, Avallone Bice, Marco Corsi Massimiliano, Sarubbi Berardo, Calabrò Raffaele, Salvatore Paola, Ciccodicola Alfredo, Napoli Claudio

Abstract excerpt

BACKGROUND: Pathological angiogenesis represents a critical issue in the progression of many diseases. Down syndrome is postulated to be a systemic anti-angiogenesis disease model, possibly due to increased expression of anti-angiogenic regulators on chromosome 21. The aim of our study was to elu...

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Identifiers

PMID: 20836844
DOI: 10.1186/1755-8794-3-40
PMCID: PMC2949777

Genes

CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20836844-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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