Article
The Notch gene, adhesion, and developmental fate in the Drosophila embryo.
The New biologist - 1 Jul 1990
Greenspan R J
Abstract excerpt
The Notch locus in Drosophila encodes a transmembrane protein required for the determination of cell fate in ectodermal cells. When these cells are faced with a choice of two possible fates, Notch enables some of them to advance from the fate that represents a "default" state. The decision appears to involve both an interaction between cells and the presence of the Notch product on the surface of those advancing...
Topics
- Animals
- Cell Adhesion
- Cell Adhesion Molecules
- Drosophila
- Drosophila Proteins
- Insect Hormones
- Membrane Proteins
- Mutation
- Receptors, Notch