Article
Callosal microstructural abnormalities in Alzheimer's disease and alcoholism: same phenotype, different mechanisms.
Psychiatry research - 30 Oct 2010
Pitel Anne-Lise, Chanraud Sandra, Sullivan Edith V, Pfefferbaum Adolf
Abstract excerpt
Magnetic resonance (MRI) and diffusion tensor imaging (DTI) data were acquired in 13 Alzheimer's disease (AD) patients, 15 elderly alcoholics, and 32 elderly controls. Midsagittal area, length, dorsoventral height, fractional anisotropy (FA), and mean diffusivity (MD) of the total corpus callosum and volume of the lateral ventricles were measured; area, FA, and MD were also determined for the callosal genu, body,...
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