Article
Vascular endothelial growth factor gene polymorphisms and ovarian cancer survival.
Gynecologic oncology - 1 Dec 2010
Lose Felicity, Nagle Christina M, O'Mara Tracy, Batra Jyotsna, Bolton Kelly L, Song Honglin, Ramus Susan J, Gentry-Maharaj Aleksandra, Menon Usha, Gayther Simon A, Pharoah Paul D P, Kedda Mary-Anne, Spurdle Amanda B
Abstract excerpt
OBJECTIVES: We sought to evaluate the effect of polymorphisms in the VEGF (Vascular Endothelial Growth Factor) gene on overall survival in ovarian cancer patients. METHODS: A sample of 319 women diagnosed with primary invasive epithelial ovarian cancer in Australia between 1985 and 1997, recruited as incident cases, were genotyped for four VEGF single nucleotide polymorphisms (three tagSNPs and one functional...
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